Endocrine Abstracts

The prevalence of overweight children and adolescents is one of the most important public health challenges today. The impact of this early obesity extends into adulthood: increased mortality and morbidity from a variety of conditions and adverse socio-economic consequences. No single approach to the treatment of childhood overweight has been demonstrated to be more effective than another. Challenges faced in managing obese child is selecting the approach that will be adhered ...

The incidence of endogenous Cushing’s syndrome (CS) is ~2–5 new cases per million people per year; ~10% of these new cases occur in children. The most common cause of endogenous CS in children is an ACTH-secreting pituitary adenoma (~75% of all cases in children older than 7 years). CS is still diagnostic and therapeutic challenge, especially in childhood. One of the most important diagnostic steps is thinking about it. The evaluation of children with the clinical ma...